Yankees vs. Blue Jays prediction, odds, line, time: 2026 MLB picks for Saturday, Aug. 22 by proven model

This page may contain affiliate links. If you click and sign up, make a deposit, or place a wager, we may earn a commission at no additional cost to you. SportsLine's model simulated Toronto vs. New York on Saturday 10,000 times and revealed its MLB picks today Aug 22, 2026 at 12:07 pm ET • 2 min read The Saturday MLB schedule gets underway with a critical AL East matchup as the New York Yankees (73-55) host the Toronto Blue Jays (63-67). New York currently holds the top AL wild-card slot, while the Blue Jays are 1.5 games out of the final playoff spot. Ace Dylan Cease (7-5, 2.42 ERA) is on the hill for the Blue Jays, and he'll be countered by lefty Ryan Weathers (5-7, 3.56 ERA) for the Yankees. Visit our DraftKings promo code review and get $150 in bonus bets instantly as a new user after $5+ in wagers here:First pitch from Yankee Stadium is set for 1:35 p.m. ET. The Yankees vs. Blue Jays odds are deadlocked with Toronto and New York both listed at -106 (risk $106 to win $106), while the over/under is 6.5 Before making any Blue Jays vs. Yankees picks, be sure to see the Yankees vs. Blue Jays predictions and betting advice from SportsLine's proven computer model. The SportsLine Projection Model simulates every MLB game 10,000 times and entered Week 22 of the MLB season on a sizzling 49-31 run on all top-rated MLB picks. It also excelled at making home run prop picks in 2025, returning nearly 30 units of profit. Anyone following its MLB betting picks at sportsbooks and on betting sites could have seen strong returns. Now, the model has set its sights on Blue Jays vs. Yankees and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model's picks. Here are several MLB odds and betting lines for Yankees vs. Blue Jays:Yankees vs. Blue Jays money lineBlue Jays -106, Yankees -106Yankees vs. Blue Jays over/under6.5 runsYankees vs. Blue Jays run line Blue Jays -1.5 (+165)Yankees vs. Blue Jays picksSee picks at SportsLineYankees vs. Blue Jays streaming Fubo (Try for free) New to sports trading? Visit our Kalshi promo code review to see their latest offers and get started. Top Yankees vs. Blue Jays predictions After 10,000 simulations of Blue Jays vs. Yankees, the model is going Over 6.5 combined runs for over/under betting. A strong pitching matchup has the total lower for this game, but the Blue Jays have slightly trended to the Over this season. They are 32-30 to the Over on the road, and they've cleared the total in 53% of games where the over/under was 7 runs or fewer.The model projects that Ben Rice and Luis Garcia have the highest probabilities of driving a run in for the Yankees, while George Springer and Kazuna Okamoto have the highest chances for the Blue Jays. The model projects the teams to combine for 8.3 total runs as the Over hits 67% of the time. Get the Blue Jays vs. Yankees money-line pick at SportsLine.New to sports trading? Visit our Kalshi promo code review and get a $25 trading bonus after $25+ in trades with the Kalshi promo code CBSSPORTS:How to make Yankees vs. Blue Jays picksAfter simulating every pitch of Blue Jays vs. Yankees 10,000 times, the model also says one side of the money line has all the value. You can get that pick at SportsLine. So who wins Blue Jays vs. Yankees, and which side of the money line has all the value? Visit SportsLine now to see which side you need to jump on, all from the model that has crushed its MLB picks, and find out.