This page may contain affiliate links. If you click a link and sign up, make a deposit, place a wager, or make a trade, we may earn a commission at no additional cost to you. The Week 4 NFL schedule features a 14-game slate on Sunday, headlined by matchups like Eagles vs. Rams, 49ers vs. Broncos and Panthers vs. Lions. Our Week 4 NFL betting guide previews every game on Sunday and gives step-by-step instructions to claim the top online sportsbook promos from the best betting apps. It also explores Week 4 NFL betting trends, breaks down the NFL betting terms you'll need to know, and provides a general introduction to NFL wagering. Get $150 in bonus bets after making a $5 wager with the latest DraftKings promo code:San Francisco is off to a 3-0 start this season heading into its matchup against Denver (2-1) on Sunday. The 49ers are 2.5-point favorites in the Week 4 NFL odds, while the over/under is 47.5. Carolina (1-2) will try to get back to the .500 mark in primetime on Sunday Night Football against Detroit (2-1). Our Week 4 NFL betting guide highlights many of the top NFL betting trends, previews every game on the Week 4 NFL schedule, and provides step-by-step instructions to claim the latest online sportsbook promos from the best betting apps to boost your bankroll. You can use any of the Week 4 NFL lines to score nearly $3,000 in sign-up bonuses by using these top NFL betting promos. Use the FanDuel promo code to get $250 in bonus bets for NFL games:If you're wondering how to bet on the NFL, or where to bet on NFL Week 4, our Week 4 NFL betting preview also gives you all the details for claiming some of the best NFL promo codes, including the FanDuel promo code, DraftKings promo code and bet365 bonus code. You can use these sign-up bonuses to significantly boost your bankroll and receive an intro to NFL wagering that gives you everything you need to know before you begin NFL betting. Bet on the NFL with the BetMGM bonus code CBSSPORTS for up to $1,500 in bonus bets:How to bet on NFL Week 4There have been many surprisingly slow starts in the 2026 NFL season, with the Texans, Chargers and Buccaneers among the 0-3 teams, and how they approach what could be a more desperate Week 4 situation is something to consider when exploring Week 4 NFL bets. With another full 16-game NFL schedule in Week 4, there will be plenty of betting opportunities on markets such as winners, spreads, totals, game props and player props for online sports betting apps. Anyone looking for how to bet on NFL Week 4 can take advantage of a variety of sportsbook promos and bonuses as the 2026 NFL season moves into October. Online sports betting is now legal in more than 30 states, plus Washington D.C. and Puerto Rico, and it's simpe and straightforward to register for online betting sites like FanDuel, DraftKings, BetMGM, bet365, Caesars, Hard Rock Bet and Fanatics Sportsbook. With the NFL regular season underway, top sports betting apps are offering sportsbook promos that could help you boost your bankroll going into the first full month of NFL action.Bet on every NFL game by claiming the latest DraftKings promo code, where new users get $150 in bonus bets after your first $5 wager: 2026 NFL Week 4 scheduleSunday, Oct. 4Colts vs. Commanders (+3.5, 47.5), 9:30 a.m. ET from LondonPatriots at Bills (-7, 48.5), 1 p.m. ETJets at Bears (-3.5, 42.5), 1 p.m. ETJaguars at Bengals (-2.5, 51.5), 1 p.m. ETCardinals at Giants (+1.5, 44.5), 1 p.m. ETRams at Eagles (+3, 45.5), 1 p.m. ETPackers at Buccaneers (+3.5, 39.5), 1 p.m. ETTitans at Ravens (-11.5, 43.5), 1 p.m. ETCowboys at Texans (-2.5, 47.5), 1 p.m. ETDolphins at Vikings (-11.5, 38.5), 4:05 p.m. ETChiefs at Raiders (+4.5, 47.5), 4:25 p.m. ET Broncos at 49ers (-3, 46.5), 4:25 p.m. ETRams at Seahawks (-7, 42.5), 4:25 p.m. ETLions at Panthers (+3.5, 50.5), 8:20 p.m. ETMonday, Oct. 5Falcons at Saints (-3, 48.5), 8:15 p.m. ETNFL Week 4 game previewsColts vs. Commanders previewColts vs. Commanders kickoff9:30 a.m. ET in LondonColts vs. Commanders spreadColts -3.5Colts vs. Commanders over/under47.5Colts vs. Commanders money lineIND -180, WAS +150The first Sunday morning international game of the 2026 NFL season takes place this week with the Indianapolis Colts playing the Washington Commanders at Tottenham Hotspur Stadium in London, England. Both teams are coming off upset victories, with the Colts defeating the Texans, 19-17, and the Commanders knocking off the defending Super Bowl champion Seattle Seahawks, 33-31. Washington won despite Marcus Mariota starting for Jayden Daniels (elbow). Seattle outgained Washington 437-258, but the Commanders capitalized on three forced turnovers. Daniel Jones threw for 235 yards for the Colts last week, and both teams enter at 1-2. Claim $200 in bonus bets with a $10 bet by signing up for bet365 Sportsbook:Patriots vs. Bills preview Patriots vs. Bills kickoff1 p.m. ETPatriots vs. Bills spreadBills -7 Patriots vs. Bills over/under48.5Patriots vs. Bills money lineBUF -300, NE +240The Bills play their third straight game in their new stadium, and they haven't lost in it yet. The Bills are coming off a 24-16 win over the Chargers last week to improve to 3-0, and they have the No. 1 scoring offense at 33.7 points per game this season. Meanwhile, the Patriots' offense has struggled coming off their Super Bowl loss. They are tied with the Dolphins for the worst scoring offense at 12 points per game, and New England is coming off a 35-6 loss to the Jaguars. Drake Maye is averaging just 195 passing yards per game. Meanwhile, Josh Allen has five passing and six rushing touchdowns through three games. Sign up at Hard Rock Bet and get $100 in bonus bets:Jets vs. Bears preview Jets vs. Bears kickoff1 p.m. ETJets vs. Bears spreadBears -3.5Jets vs. Bears over/under42.5Jets vs. Bears money lineCHI -175, NYJ +145The Bears' offense didn't lose a beat in the first game without Caleb Williams this season. Case Keenum completed 24 of 34 passes for 247 yards and two touchdowns and rushed for a score in a game where the defense forced three turnovers as Chicago defeated the Eagles, 27-7. Meanwhile, the Jets hung around with the Lions but lost 31-24 on the road as they play their third straight NFC North opponent. The Jets (1-2) lost 20-17 to the Packers in overtime in Week 2. The Bears are 2-1 and Williams (hamstring) will miss this contest as well. Use the FanDuel promo code to get $250 in bonus bets for NFL games:Jaguars vs. Bengals previewJaguars vs. Bengals kickoff1 p.m. ETJaguars vs. Bengals spreadBengals -2.5Jaguars vs. Bengals over/under51.5Jaguars vs. Bengals money lineCIN -142, JAC +120The Jaguars and Bengals have the highest over/under (51.5 points) of the Week 4 NFL schedule, which could make this the game of the week if you're a fan of offense. Both teams are led by former No. 1 overall picks at quarterback in Jacksonville's Trevor Lawrence and Cincinnati's Joe Burrow. The Jaguars are coming off a 35-6 win over defending AFC champion New England, while the Bengals scored 27 points in a 30-27 loss to the Steelers. The Bengals defeated the Jaguars, 31-27, last season. Both teams are 2-1 this season. Bet on the NFL with the BetMGM bonus code CBSSPORTS for up to $1,500 in bonus bets:Giants vs. Cardinals preview Giants vs. Cardinals kickoff time:1 p.m. ETGiants vs. Cardinals spread:Arizona -1Giants vs. Cardinals Over/Under:44.5Giants vs. Cardinals money line:New York -108, Arizona -113With Jameis Winston stepping in as the starter after Jaxson Dart suffered a season-ending knee injury, the Giants scrapped out a 12-7 win over the Titans to improve to 2-1. Now they'll welcome the Cardinals to MetLife Stadium as they come off a 36-30 loss to the 49ers. Both teams are 2-1 against the spread so far on the season and have trended towards the Under (2-1) as well. The Giants traded for JJ McCarthy on Monday as an insurance policy, but this is presumably Winston's ship to guide. 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This is a potential get-right game for the winner, but the loser might have some soul-searching to do given the talent on these respective rosters. Claim $200 in bonus bets with a $10 bet by signing up for bet365 Sportsbook:Buccaneers vs. Packers preview Buccaneers vs. Packers kickoff time:1 p.m. ETBuccaneers vs. Packers spread:Green Bay -4Buccaneers vs. Packers Over/Under:39.5Buccaneers vs. Packers money line:Tampa Bay +162, Green Bay -195Here are two more teams that began the year as NFC playoff hopefuls, but the Packers and Buccaneers are off to even more abysmal starts. Green Bay's lone win was the result of a Jets collapse, and last week the Packers were embarrassed by the Falcons on Thursday Night Football. Meanwhile, Tampa Bay is off to a 0-3 start, and starting quarterback Baker Mayfield is out at least three weeks after dislocating the thumb on his throwing hand. Jalon Daniels will start for the Buccaneers in his absence. Claim the Fanatics Sportsbook promo code here to get $350 in FanCash:Ravens vs. Titans previewRavens vs. Titans kickoff time:1 p.m. ETRavens vs. Titans spread:Baltimore -11.5Ravens vs. Titans Over/Under:43.5Ravens vs. Titans money line:Baltimore -714, Tennessee +509Fresh off the Miracle at Maracana, the Ravens will host the Titans for an AFC showdown on Sunday. Tyler Loop's 56-yard field goal as time expired gave Baltimore a 34-31 win over the Cowboys in Rio de Janeiro to improve to 2-1. Meanwhile, the Titans dropped to 0-3 with a 12-7 loss to the Giants, punctuated by a brutal Cam Ward interception in the endzone with a chance to take the lead. Robert Saleh's defense is top 10 in the NFL, but the Tennessee offense can't get anything going at the moment. 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Titans vs. Ravens The Under has hit in seven of the last 10 meetings between the Titans and Ravens. The road team is 5-0-1 ATS in the last six meetings.Rams vs. EaglesThe Eagles are 6-0 ATS in their last six games as an underdog. The Over is 8-1 in Los Angeles' last nine games on the road. Packers vs. BuccaneersThe Over is 4-0 in Green Bay's last four games in October. The underdog is 4-0 ATS in the past four meetings between the Packers and Buccaneers. Jets vs. BearsThe Under is 6-1 in Chicago's last seven home games. The Jets are 2-1 ATS this season. Patriots vs. BillsThe Bills are 3-1 ATS in their last four meetings with the Patriots. The Patriots are 5-0 ATS in their last five games following a loss. Cardinals vs. Giants The Cardinals are 5-0 ATS in their last five meetings with the Giants. The Over is 6-1 in New York's last seven games overall. Cowboys vs. TexansThe road team is 5-0 ATS in the last five meetings between the Cowboys and Texans.The Over is 7-1 in Dallas' last eight games on the road. Dolphins vs. Vikings The Under is 5-0 in Minnesota's last five games as a favorite. The Vikings are 7-0-1 ATS in their last eight games. Chargers vs. SeahawksThe Over is 7-1 in Seattle's last eight meetings against an opponent with a losing record. The underdog is 7-0 ATS in the last seven meetings between these two teams. Broncos vs. 49ers The Over is 5-0 in San Francisco's last five games when playing as the favorite. The home team has covered the spread in four straight meetings. Chiefs vs. RaidersThe Raiders are 4-1 ATS in their last five meetings with the Chiefs. The Under is 5-1 in Kansas City's last six road games. Lions vs. Panthers The home team is 4-0 ATS in the last four meetings. The Panthers are 11-1 ATS in their last 12 games following an ATS loss. Falcons vs. Saints The Saints are 8-1 ATS in their last nine games overall. The Under is 3-0 in the last three meetings between the Saints and Falcons. Bet on the NFL by claiming the latest DraftKings promo code, where new users get $150 in bonus bets after your first $5 wager: NFL Week 4 betting options and wagers Popular wagers Definition Money lineBetting on the winner of the gameSpreadThe number of points the favorite is projected to win byOver/underThe projected number of total points in the gameTeam totalBetting on the projected number of points for an individual teamAnytime touchdown scorerBetting on a player to score a touchdownPlayer propsBetting on various player stats like total passing yards or rushing attemptsParlaysCombining multiple bets into one ticketSeason win totalBetting on how many wins a team records in the regular seasonDivision winnerBetting on a team to win its divisionSuper Bowl winnerBetting on a team to win the Super BowlAwardsBetting on awards like MVP, Coach of the Year, etc.Make/miss playoffsBetting on a team to make or miss the postseasonMoney lineA money line bet is the simplest way to bet on Week 4 NFL games, as it only requires bettors to pick the winner. If a team is -300 to win, a $300 bet pays out $100, while a $100 bet on a +300 money line pays out $300. SpreadThe spread levels the playing field between teams, as it is the number of points a team is expected to win by. A team favored by 9.5 points needs to win by at least 10 points to cover the spread, while the underdog needs to keep the margin to nine points or fewer (or win outright) to cover the spread. Over/underThis is the total number of expected points scored in the game. An over/under of 39.5 requires 40 points to go Over and 39 points or fewer to go Under. Team totalBettors can also wager on the total number of points for each individual team. A team with an over/under of 19.5 points needs to score at least 20 points to go Over its team total. Anytime touchdown scorerOne of the most popular NFL markets is the anytime touchdown scorer market. It is simply a wager on a player to score a touchdown at any point during his respective game. Player propsThere are various player props for every NFL game, including markets like passing yards, passing attempts, total receptions, total carries and more. ParlaysParlays combine multiple bets into one wager, so the odds are drastically longer than single wagers. However, every leg of the parlay must win in order for the bet to payout. Season win totalEvery team has a season win total, which is the expected number of wins for that team during the 2026-27 regular season. Those win totals will be updated after every game, and many of them have changed drastically since the season began. Division winner Some NFL bettors are particularly familiar with certain divisions, and the division winner market allows them to put that knowledge to use. Each division has its own set of odds, which will change every week as standings get updated. Super Bowl winnerAnother popular NFL betting market is the Super Bowl winner. It is the biggest game of the year, so bettors often want to place wagers on teams early in the season. AwardsThere are various NFL awards to wager on, including MVP, Offensive Player of the Year, Defensive Player of the Year, Rookie of the Year, Coach of the Year and more. Make/miss playoffsEvery team has odds to make or miss the postseason. Some teams are heavily favored to make the playoffs, while other teams are longshots to make the field. Bet on the NFL with the BetMGM bonus code CBSSPORTS for up to $1,500 in bonus bets:2026 Super Bowl odds heading into Week 4Super Bowl odds will fluctuate throughout the season. According to the latest Super Bowl odds at FanDuel Sportsbook, the Bills are the +650 favorites heading into Week 4. The Rams are priced at +700, followed by the Seahawks (+950) and Ravens (+950). Other notable Super Bowl contenders include the 49ers (+1000), Chiefs (+1200), Lions (+1700), Eagles (+1700) and Jaguars (+1800). Click on the odds (via FanDuel) to wager on the Super Bowl winner now.TeamOddsBills+650Rams+700Seahawks+950Ravens+95049ers+1000Chiefs+1200Eagles+1700Lions+1700Jaguars+1800Bengals+1900Broncos+2000Bears+2200Vikings+2200Cowboys+2700Texans+3000Patriots+3300Packers +5000Colts+5500Saints+6000Commanders+8000Chargers+8000Raiders+8000Falcons+10000Panthers+10000Buccaneers+10000Steelers+10000Giants+12500Jets+20000Browns+25000Cardinals+35000Titans+60000Dolphins+100000NFL Week 4 player props Commanders wide receiver Terry McLaurin: Over/Under 55.5 receiving yards (SportsLine's model projects McLaurin will finish with 72.1 receiving yards) Bills QB Josh Allen: Over/Under 236.5 passing yards (SportsLine's model projects Allen will finish with 242.1 passing yards) Ravens QB Lamar Jackson: Over/Under 18.5 passing completions (SportsLine's model projects Jackson will finish with 14.3 completions) Cowboys WR CeeDee Lamb: Over/Under 76.5 receiving yards (SportsLine's model projects Lamb will finish with 91.8 receiving yards) Patriots QB Drake Maye: Over/Under 228.5 passing yards (SportsLine's model projects Maye will finish with 260.3 passing yards) Bengals WR Ja'Marr Chase: Over/Under 79.5 receiving yards (SportsLine's model projects Chase will finish with 84.9 receiving yards) Rams WR Davante Adams: Over/Under 74.5 receiving yards (SportsLine's model projects Adams will finish with 96.8 receiving yards) Eagles QB Jalen Hurts: Over/Under 24.5 rushing yards (SportsLine's model projects Hurts will finish with 32.9 rushing yards) Packers WR Matthew Golden: Over/Under 57.5 receiving yards (SportsLine's model projects Golden will finish with 40.2 receiving yards) Chiefs QB Patrick Mahomes: Over/Under 241.5 passing yards (SportsLine's model projects Mahomes will finish with 283.8 passing yards) Raiders RB Ashton Jeanty: Over/Under 61.5 rushing yards (SportsLine's model projects Jeanty will finish with 50.9 rushing yards) 49ers QB Brock Purdy: Over/Under 234.5 passing yards (SportsLine's model projects Purdy will finish with 275.4 passing yards) Seahawks WR Jaxon Smith-Njigba: Over/Under 6.5 receptions (SportsLine's model projects Smith-Njigba will finish with 8.7 receptions) Panthers QB Bryce Young: Over/Under 21.5 passing completions (SportsLine's model projects Young will finish with 18.4 completions) Bet NFL props and claim $200 in bonus bets with a $10 bet by signing up for bet365 Sportsbook here:How NFL betting payouts work NFL betting payouts are determined using American odds, with the minus sign (-) indicating the favorite and the plus sign (+) indicating the underdog. The total payout includes the original stake along with the potential profit, and they vary depending on the type of market. Standard spreads are -115 at sportsbooks, meaning bettors need to wager $115 to win $100 on a successful bet. Parlays can increase payouts exponentially, but every leg of the parlay needs to win in order for the bet to win. A standard two-leg parlay of -110 wagers pays +264, with a winning $100 bet resulting in a $264 profit. Underdogs pay more than favorites because the betting market considers those teams less likely to win.
How to bet on 2026 NFL Week 4: Betting odds, game previews, trends, tips, schedule, sportsbook promos, offers
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