The Red Devils return from the final international break of 2026 to face the daunting prospect of visiting arch-rivals Liverpool in the Premier League on Sunday, November 22.Pochettino inherits a side with just one win in 10 top-flight games this term, a string of results that have left Man Utd in the relegation zone.The Argentine’s style of play centres around a high-press and an ability to build from the back - two things United have struggled with so far this season.In goal, Senne Lammens is established first-choice and that is unlikely to change with Pochettino’s arrival.Interestingly, Pochettino might be tempted to copy Carrick and play Leny Yoro at right-back. Out of possession the right-back tucks in to form a three-man defence in Pochettino’s favoured system, but with an actual left-back fit, there is little reason to play defenders out of position.For that reason, Diogo Dalot will likely start at right-back, with a much more simple defensive approach. Yoro and Ayden Heaven in the heart of defence could give United a bit more pace than a backline featuring Harry Maguire, but the experience of Lisandro Martinez may be hard to ignore as Pochettino balances a squad lacking in confidence.Patrick Dorgu seems a strong fit at left-back. Antonee Robinson loved to get forward for Pochettino while on USA duty, and the wing-back is a proven attacking threat.With the USA, Pochettino has settled on a 4-3-3 formation, with the midfield featuring a sitting player behind two more proactive team-mates.Read MorePochettino’s immediate issue with the United squad will be the fact that there is no clear candidate as a holding midfielder. The injured Baleba does well at screening the backline, but his strengths rely on driving forward with the ball.It is a similar story for Andrey Santos - a midfielder that is still unsure whether his best position is as a No6, 8, or 10.The deep-lying playmaker role is a battle between Kobbie Mainoo and Youri Tielemans. Pochettino has shown a tendency to trust young, talented players, so it would not be a surprise to see the former Tottenham manager try and work his magic with Mainoo.Tielemans could play the box-to-box role alongside Mainoo, offering experience during the transition to Pochettino’s ideal approach.While Pochettino has utilised a deeper player in the middle of the park with the USA, it is likely that he will instead have to build a more attacking midfield at United.Matheus Cunha looks a good fit on the left wing as a creative spark, while Bryan Mbeumo’s pace down the right wing would allow Pochettino to create a similar attacking shape to his USA side.However, with United’s striking options limited, it would not be a surprise to see Mbeumo lead the line, with Amad Diallo playing instead on the right.Predicted Manchester United XI vs Liverpool (4-2-3-1): Lammens; Dalot, Yoro, Martinez, Dorgu; Tielemans, Mainoo; Amad, Fernandes, Cunha; Mbeumo
How Manchester United could line up in Mauricio Pochettino’s first game against Liverpool
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